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Beilstein J. Org. Chem. 2015, 11, 323–327, doi:10.3762/bjoc.11.37
Graphical Abstract
Figure 1: Naturally occurring 5-hydroxylated 3-acyltetramic acids.
Scheme 1: Synthesis of model tetramic acids.
Scheme 2: Synthesis of hemiaminal ethers and deprotection of the tetramic acids.